YOGURT| E-liquid 10ml with nicotine

YOGURT


The following table summarizes the results of the analyses on the product “YOGURT| E-liquid 10ml with nicotine”.


TOXICITY

RESISTANCE

INFLAMMATION

approved
approved
approved


Here following the detailed results of every single analysis.
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Toxicity Testing

The tested e-liquid is turned into vapor using an instrument that simulates the real functioning of an electronic cigarette (the so-called Vaping Machine). The result of the evaporation is an aerosol that is placed in contact with two layers of cells that mimic the pulmonary alveolus . Depending on the toxicity of the aerosol, the test will measure the percentage of cells not surviving the treatment. Please, click here for further details about the test. The chart below shows both the toxicity level of the analyzed e-liquid and that of a traditional cigarette* on the two cellular layers. The threshold value is the percentage above which the producer is recommended to reformulate the product or to withdraw it from the market. One half of the cells dies when placed in contact with a compound with 50% toxicity.
The lung epithelium is a tissue composed of cells that are specialized to protect and to allow gas exchange. The lung epithelium is the alveolus portion that is in contact with the air.
The vascular endothelium is a tissue composed of cells that are specialized to be the proper covering of the blood and lymph vessels. At pulmonary level it represents the portion of the alveolus that is in contact with blood.
For more details, please click here.

The values can assume three different meanings:

GREEN: no significant toxic effects observed.

ORANGE: results of the statistical analysis are significant, but below the threshold value: only an occasional use is recommended.

RED: threshold value exceeded, it’s recommendable to stop using the product and the company is suggested to withdraw the e-liquid from production.

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Electrical resistance test

The cells that mimic the pulmonary alveolus are so similar to those actually present in human body that are tightly stick together. It means that there is a complete adhesion among cells and so a maximum resistance to the passage of electric current can be observed. Depending on the toxicity of the e-liquid, the cell adhesion could reduce causing the loss of contact among cells. The test assesses the permeability of cells to the passage of electricity: the higher the detected passage of electricity is (less than 400 Ohm resistance), the greater will be the cellular damage and therefore the toxic effect of the e-liquid. Maximum resistance values (higher than 400 Ohm) correspond to healthy cells with excellent adherence. Please, click here for further details about the test.

Transepithelial Electrical Resistance (Ohm)

barraresistenza
645
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Inflammation assessment

The tested e-liquid is turned into vapor using an instrument that simulates the real functioning of an electronic cigarette (the so called Vape Machine). The result of the evaporation is an aerosol that is placed in contact with two layers of cells that mimic the pulmonary alveolus. When in contact with toxic substances, cells defend themselves through an inflammatory process that produces inflammatory mediators. The test quantifies the amount of the inflammatory mediators released by the cells to assess the toxicity of the e-liquid. The chart below shows a comparison between e-liquid and traditional cigarette. Please, click here for further details about the test. The threshold value is the percentage above which the producer is recommended to reformulate the product or to withdraw it from the market. One half of the cells dies when placed in contact with a compound with 50% toxicity.
The lung epithelium is a tissue composed of cells that are specialized to protect and to allow gas exchange. The lung epithelium is the alveolus portion that is in contact with the air.
The vascular endothelium is a tissue composed of cells that are specialized to be the proper covering of the blood and lymph vessels. At pulmonary level it represents the portion of the alveolus that is in contact with blood.
For more details, please click here.

The values can assume three different meanings:

GREEN: no significant toxic effects observed.

ORANGE: results of the statistical analysis are significant, but below the threshold value: only an occasional use is recommended.

RED: threshold value exceeded, it’s recommendable to stop using the product and the company is suggested to withdraw the e-liquid from production.

*Ref. Cervellati et al., 2014

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F.A.Q

What does the symbols mean?

approved APPROVED. No significant toxic effects were assessed in the e-liquid, under the analysis conditions tested on the model.
attention ATTENTION. The e- liquid is found to have toxic effects under the analysis conditions tested on the model, but below the threshold value. As a precautionary measure, an occasional use of the product is recommended.
not approved NOT APPROVED. The e-liquid is found to have significant toxic effects under the analysis conditions tested on the model and it means that the result of the analysis exceeds the threshold value. As a precautionary measure, it’s recommended that customer stop using the product and that the producer withdraw it from the market.

Which nicotine levels have been analyzed?

The results refer to e-liquids at the highest concentration of nicotine (18mg/ml). The international scientific community widely demonstrated that the nicotine contained in an e-liquid does not represent a relevant toxic element.

Why is it necessary to test every aromatic variant?

The international scientific community identified the aromatic component of an e-liquid as the main source of potential toxicity. Since the products differ mainly for the aromatic component, it’s necessary to analyze every variant to guarantee the healthiness of the whole range.

If an e-liquid obtain the “Approved” mark on “ClearStreamOnward”, does it mean that it is health-safe?

The approved e-liquids are those passing all three tests with flying colors: toxicity, resistance and inflammation. In this case, the e-liquid is reasonably safe for 99% of the consumers in proper conditions of use. A certain percentage of people could be intolerant to liquids for pathological reasons and in these cases we recommend to consult a doctor.

Where can I get more information about the results of scientific research and the effects of vaping on health?

The site the-ecig-science.org is a blog of TRUSTiCERT in several languages that is constantly updated on the latest scientific discoveries in the field of electronic cigarette. Follow "The E-cig Science" on Facebook and Twitter.